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If your skin transformed into tissue paper (like…overnight?!), welcome to the club you didn’t ask to join. Here’s what got you here: As estrogen declines, women lose up to 30% of their collagen in the first five years after menopause, while years of sun exposure break down elastin — the protein that gives skin its snap.
Want out of the club? We asked Dr. Ava Mainieri, PhD what actually helps:
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Retinoids: AKA the gold standard for rebuilding collagen, with decades of research behind them
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Topical estriol: Helps address the hormonal changes that make skin thinner and less resilient
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Lactic acid or urea: Look for these ingredients in body lotions to help smooth skin and boost hydration
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Sunscreen: Think of it as protecting your skincare progress (PSA: You can't out-cream ongoing UV damage!)
Menopause-related skin changes often start with shifting hormones, so the best treatment goes beyond skincare. A Midi Clinician can prescribe solutions — including prescription skincare and hormone therapy, if appropriate. |
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What's the Connection Between Menopause and High Cholesterol? |
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Estradiol vs Estrogen: What's the Difference and Which Do You Need? |
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How Fast Does Tirzepatide Work? The Timeline Women Should Know |
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Midi Diaries |
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“Midi gave me my sex drive back.” - Kimberly S., Midi patient |
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When I reached perimenopause, my sleep completely changed. I started waking up several times a night, drenched in sweat and with a racing heart — even though I didn’t feel anxious about anything. My sex drive also dropped, and reaching orgasm became much harder than before.
I reached out to two gynecologists, but both refused to prescribe hormone therapy. That’s when I booked a visit with Midi. The whole process was so easy — no driving, no taking time off work, just a convenient virtual visit from home.
For the first time, a clinician actually normalized what I was going through. She started me on HRT, which has made a huge difference in my sleep, and she added testosterone.* I have more energy, and my sex drive is back to where it used to be, which is such a relief. |
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Missed last week’s newsletter? |
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Catch up on past editions of the Midi Weekly and subscribe to get expert tips, science-backed solutions, and the latest menopause news straight to your inbox. |
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